Vioxx? Primer

rofecoxib \rofecoxib\ (Chem. & Med.)
   A chemical substance (C17H14O4S, molecular weight 314.36)
   used in medicine as an analgesic to alleviate pain and
   inflammation; it is a synthetic compound, and is marketed by
   Merck & Co. under the trade name Vioxx, in tablets giving
   dosages of 12.5 or 25 milligrams. It is classed as a
   non-steroidal anti-inflammatory drug (NSAID). Chemically, it
   is 4-[4-(methylsulfony)phenyl]-3-phenyl-2(5H) furanone. Its
   chemical structure contains two phenyl rings and a furanone
   ring. It is believed to act by inhibition of prostaglandin
   biosynthesis, through inhibition of the enzyme
   cyclooxygenase-2 (COX-2); unlike aspirin, it does not
   inhibit cyclooxygenase-1.
   [PJC]

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Off-site Vioxx Links, User Submitted

The following links have been collected through user bookmark submission in the Vioxx category. Please note, because these resources are off-site we cannot guarantee the accuracy or quality of any information.

Fri Nov 28

• Vioxx Heart Attack and Stroke Risk - Vioxx Legal News and Information: On September 30, 2004, Merck & Co., the manufacturer of the blockbuster arthritis drug Vioxx (rofecoxib), announced the voluntary, worldwide recall of Vioxx....

Tue Nov 25

• Michigan asbestos fraud

Fri Nov 21

• Why Obama Should Keep His BlackBerry - WSJ.com: Cardinal Richelieu famously said, "If one would give me six lines written by the hand of the most honest man, I would find something in them to have him hanged."

Tue Nov 18

• Research Confirms Vioxx Increases Risk of Heart Attack | YourMedicament: New research from a long-term study of individuals taking the arthritis drug known as Vioxx offers confirmation that the drug increases the risk of stroke
• Wyeth v. Levine Could Endanger Your Health - Forbes.com: Field preemption needed

Fri Nov 14

• THE PREACHER WHO'S RAISING HELL WITH MERCK - August 8, 2005

Tue Nov 11

• Contrary Tales of Vioxx Role in Texan's Death - New York Times
• $253.4 Million Verdict in First Merck Vioxx Trial

Mon Oct 27

• SSRN-Procedura l Justice in Nonclass Aggregation by Elizabeth Burch

Sun Oct 26

• Where can I get more information on Vioxx?: You can obtain more information from Merck at: www.merck.com and www.vioxx.com, or (888) 36VIOXX ((888) 368-4699). To find out more about Vioxx from the FDA Visit the FDA's Drug Information web page at: www.fda.gov/cd er.

Fri Oct 24

• Long-Term Data on Rofecoxib Confirm Cardiovascular Risks - Physician's First Watch: use of rofecoxib was associated with "an early increase in risk [for the combined incidence of myocardial infarction, stroke, and death from cardiovascular , hemorrhagic, and unknown causes] that seems to persist for about 1 year after 3 years of treatment.&quo t;

Thu Oct 23

• Tom Nesi: Best book on Vioxx
• The Federalist Society " Publications - Speech by Judge Dennis G. Jacobs: influence of attorneys
• Henry Blodget on damaging emails

Mon Oct 20

• Pfizer Settles over Bextra and Celebrex for $894 Million ? Celebrex Still on the (Black Box!) Market | InjuryBoard Cherry Hill

Off-site Vioxx Research Links

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